pharmachologic effect
Glycine is a substance that is a non-essential amino acid. Under its influence, metabolic processes in brain tissue become more active and an antioxidant effect is provided. Glycine also regulates the activity of glutamate receptors. As a result, a person’s conflict, aggressiveness, and psycho-emotional stress decrease. The patient's mood improves, the drug helps overcome symptoms of insomnia , symptoms of vegetative-vascular disorders, disorders in people who have recently suffered a traumatic brain injury or ischemic stroke . In addition, glycine reduces the degree of toxic effects of ethanol on the central nervous system.
Indications for use Glycine Bio
There are the following indications for the use of Glycine Bio:
- stressful condition , which provokes a state of psycho-emotional tension;
- deviant behavior in adolescents and children;
- deterioration of mental performance;
- diseases of the nervous system of a functional and organic nature, in which there is a high level of excitability and emotional stress;
- insomnia, other sleep disorders associated with neuroses, vegetative dystonia, various forms of encephalopathy (including those associated with alcohol abuse);
- cerebral infarction.
The drug is used in narcology for treatment during remission in encephalopathy and NS lesions.
Glycine-Bio tablets sublingual 100 mg No. 50
Compound
Active substance: glycine - 100 mg. Excipients: povidone (kollidon 25) - 4 mg, magnesium stearate - 1 mg, microcrystalline cellulose - 5 mg.
Pharmacokinetics
Easily penetrates into most biological fluids and body tissues, including the brain, and does not accumulate. It is quickly destroyed in the liver by glycine oxidase to water and carbon dioxide.
Indications for use
- stressful situations - psycho-emotional tension in stressful situations (including exams, conflict situations);
- reduced mental performance;
- deviant forms of behavior of children and adolescents;
- functional and organic diseases of the nervous system, accompanied by increased excitability, emotional instability, decreased mental performance and sleep disturbances (vegetative dystonia syndrome, neuroses, neurosis-like conditions, consequences of neuroinfections and traumatic brain injuries, perinatal and other forms of encephalopathy (including alcoholic origin) ));
- cerebral infarction;
- in narcology - as a drug that increases mental performance and reduces psycho-emotional stress during the period of remission in cases of encephalopathy, organic lesions of the central and peripheral nervous system.
Contraindications
Hypersensitivity to glycine or other components of the drug.
With caution: arterial hypotension.
Directions for use and doses
Sublingual or buccal 100 mg (in tablets or in powder form after crushing the tablets).
For practically healthy children, adolescents and adults with psycho-emotional stress, decreased memory, attention, mental performance, mental retardation, and deviant forms of behavior, glycine is prescribed 100 mg 2-3 times a day for 14-30 days.
For functional and organic lesions of the nervous system, accompanied by increased excitability, emotional lability and sleep disturbances, children under 3 years of age are prescribed 50 mg 2-3 times a day for 7-14 days, then 50 mg 1 time a day for 7-10 days. Daily dose - 100-150 mg, course dose - 2-2.6 g.
Children over 3 years of age and adults are prescribed 100 mg 2-3 times a day, the course of treatment is 7-14 days, it can be increased to 30 days, if necessary, the course is repeated after 30 days.
For sleep disorders, 50-100 mg is prescribed 20 minutes before bedtime or immediately before bedtime (depending on age).
In narcology - 100 mg 2-3 times a day for 14-30 days. If necessary, courses are repeated 4-6 times a year.
Storage conditions
In a dry place, protected from light, at a temperature not exceeding 25°C.
Keep out of the reach of children.
Best before date
3 years. Do not use after expiration date.
special instructions
In patients with a tendency to arterial hypotension, Glycine-Bio Pharmaplant® is taken in smaller doses and under the control of blood pressure; if it decreases below the usual level, the intake is stopped.
Description
A drug that improves brain metabolism.
Dosage form
Sublingual tablets are white, scored on one side and chamfered on both sides; Marbling is allowed.
Pharmacodynamics
A non-essential amino acid, a central inhibitory neurotransmitter. Improves metabolic processes in brain tissue, has an antidepressant and sedative effect. It has GABAergic, alpha 1-adrenergic blocking, antioxidant and antitoxic effects; regulates the activity of glutamate (NMDA) receptors, thereby reducing psycho-emotional stress, aggressiveness and conflict; improves social adaptation and mood; makes it easier to fall asleep and normalizes sleep; increases mental performance; reduces the severity of vegetative-vascular disorders (including during menopause), reduces the toxic effect of ethanol on the central nervous system. Effective as an adjuvant for epileptic seizures.
Side effects
Allergic reactions.
Use during pregnancy and breastfeeding
The drug is contraindicated during pregnancy and breastfeeding due to the lack of sufficient data.
Interaction
Reduces the severity of side effects of antipsychotic drugs (neuroleptics), anxiolytics, antidepressants, sleeping pills and anticonvulsants.
Overdose
There are no data on overdose.
Release form
Sublingual tablets 100 mg No. 50.
Impact on the ability to drive vehicles and operate machinery
When taking the drug Glycine-Bio, you should be careful when driving vehicles and engaging in other potentially hazardous activities that require increased concentration and speed of psychomotor reactions, taking into account the side effect profile.
Instructions for use Glycine Bio (Method and dosage)
Instructions for use provide for transbuccal or sublingual use of tablets. In stressful situations, memory deterioration, decreased performance, as well as deviant behavior , adult patients and children are advised to take 100 mg of the drug 2-3 times a day. Treatment can last up to 1 month.
If the patient is diagnosed with lesions of the nervous system , in which symptoms of excitability and emotional arousal are noted, the drug is prescribed to children under three years of age in a dose of 50 mg Glycine Bio 2-3 times a day for 1-2 weeks, children after three years of age should receive 100 mg 2-3 times a day. The course can last from 1 to 4 weeks.
If the patient has sleep disorders , then, depending on the person’s age, he needs to take 50-100 mg of the drug before going to bed.
Patients with cerebral infarction need to take 1 g of the drug in the first 3-6 hours after the onset of stroke . In the next 1-5 days you should take 1 g of the product per day, then for another 30 days. 100-200 mg three times a day.
In drug treatment practice, 100 mg is prescribed 2-3 times a day, treatment lasts from 2 to 4 weeks.
Directions for use and doses
Glycine is used sublingually or buccally (in tablets or in powder form after crushing the tablets): adults, adolescents and children over three years old - 1 tablet (100 mg), children under three years old - 0.5 tablets (50 mg).
Glycine is prescribed to practically healthy children, adolescents and adults for psycho-emotional stress, stress nervous disorders, decreased memory, attention, mental performance, mental retardation, and deviant forms of behavior: 2-3 times a day for 14-30 days.
For functional and organic lesions of the nervous system, accompanied by increased excitability, emotional lability and sleep disturbance:
- – children under three years of age: 2-3 times a day for 7-14 days, then 1 time a day for 7-10 days, daily dose - 100-150 mg, course dose - 2000-2600 mg;
- – children over three years old, adolescents and adults: 2-3 times a day for 7-14 days, daily dose - 200-300 mg, course dose - 2800-4200 mg;
On the recommendation of a doctor, the course of treatment can be increased to 30 days; if necessary, the course is repeated after 30 days.
For sleep disorders: 20 minutes before bedtime or immediately before bedtime, 0.5-1 tablet (depending on age).
For ischemic cerebral stroke: during the first 3-6 hours from the onset of stroke, 1000 mg is prescribed sublingually or buccally with one teaspoon of water, then for 1-5 days 1000 mg per day, then over the next 30 days 1-2 tablets 3 times a day.
In narcology, glycine is used as a means of increasing mental performance and reducing psycho-emotional stress during the period of remission in cases of encephalopathy, organic lesions of the central and peripheral nervous system: 1 tablet 2-3 times a day for 14-30 days. If necessary, courses are repeated 4-6 times a year.
Analogs
Level 4 ATX code matches:
Bravinton
Acefen
Carnicetine
Pyracesin
Nooclerin
Semax
Piracetam
Olatropil
Fezam
Vinpocetine
Cerebrocurin
Cavinton Forte
Calcium hopantenate
Glutamic acid
Cephabol
Olanzapine
Cerebrolysate
Pramistar
Sidnocarb
Vinpotropil
There are a number of analogues of this drug. These are the drugs Glycine Ozone , Glycised , Glycine Forte , Glycine Biotics and other drugs whose active ingredient is glycine. But only a doctor should choose the most suitable drug in each case.
Best before date
24 months
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The description of vitamin Glycine-BIO Pharmaplant is intended for informational purposes only. Before starting to use any drug, it is recommended to consult a doctor and read the instructions for use. For more complete information, please refer to the manufacturer's instructions. Do not self-medicate; EUROLAB is not responsible for the consequences caused by the use of information posted on the portal. Any information on the project does not replace consultation with a specialist and cannot be a guarantee of the positive effect of the drug you use. The opinions of EUROLAB portal users may not coincide with the opinions of the site Administration.
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