Pharmacodynamics and pharmacokinetics
Pharmacodynamics
Intellan is a preparation containing plant components rich in active substances: alkaloids, flavonoids, glycosides, amino acids, saponins, vitamins and microelements. Stimulates metabolic processes in the brain and its activity, helps improve memory and attention. Improves blood circulation and supply of nutrients to the brain, promotes the removal of metabolic products. These effects are manifested by a decrease in general fatigue. Its neurostimulating effect is used in the treatment of depressive conditions.
Ginkgo biloba extract has a vasodilating effect and improves cerebral circulation, normalizes metabolic processes in tissues, prevents the formation of free radicals, and has an antihypoxic and pronounced decongestant effect.
Centella asiatica is called the “memory herb” because its main property is to improve blood circulation in the brain and supply it with oxygen. Has a calming effect on stress and anxiety. Improves mental activity, memory and thinking processes, increases learning ability. As a result of taking it, general well-being improves, fatigue is eliminated, and sleep improves.
Herpestis monniera contains amino acids and alkaloids that indirectly affect the synthesis of GABA in brain neurons. It has a stimulating, antioxidant and anticonvulsant effect.
Coriander has antioxidant, moderate hypotensive and anticonvulsant effects. It is also used to impart taste and smell to the drug.
Essential oils of Amomum subulate have a stimulating effect.
Emblica officinalis is rich in vitamins (C, B1, B2), microelements, phosphorus, iron, calcium. Its antioxidant effect is due to its high content of vitamin C. Thanks to the presence of pectins, it reduces cholesterol . Improves the function of the cardiovascular system.
Pharmacokinetics
Due to the complex, multicomponent composition, studying pharmacokinetics is impossible.
Intellan 90 ml syrup
Instructions for use of the drug for specialists INTELLAN Trade name INTELLAN International nonproprietary name No Dosage form Syrup Composition 10 ml of syrup contain thick extracts of: Ginko biloba leaves - 50.0 mg Centella of Asian grass - 100.0 mg Herpestis monniera grass - 10.0 mg Coriander sativum – 30.0 mg Amomum subulate fruit – 30.0 mg Emblica medicinal fruit – 40.0 mg excipients: sugar, anhydrous citric acid, glycerin, sodium methyl paraben, sodium propyl paraben, sweet orange essence, tutti-frutti essence , propylene glycol, distilled water. Description Brown syrupy liquid with a characteristic aromatic odor and a specific sour-sweet, bitter taste. Pharmacotherapeutic group Other drugs for the treatment of diseases of the nervous system. ATC code N07 Pharmacological properties Pharmacokinetics: The effect of the drug is the cumulative effect of its components; all the components together cannot be traced using markers or bioresearch, so kinetic observations are not possible. Pharmacokinetic studies were carried out only for individual bioactive components. Pharmacodynamics INTELLAN is the drug of choice among brain activity stimulants. Contains pharmacologically active plants that act as stimulating nerve-transmission substances. Ginko biloba – contains flavonol glycosides and terpene lactones. Improves cerebral circulation and supply of oxygen and glucose to the brain. It has a vasodilating effect and prevents platelet aggregation. Normalizes metabolic processes and has an antihypoxic effect on tissues. Prevents lipid peroxidation and the formation of free radicals in cell membranes. It has a pronounced anti-edematous effect on brain tissue and peripheral tissues. Centella asiatica – contains triterpene glycosides, bacosides, flavonoids. Improves capillary permeability in venous insufficiency. Herpestis monniera – contains alkaloids (brahmin, herpestine), glycosides, saponins, amino acids (aspartic, glutamic, serine, terionine, alanine, glycine, leucine). Has a stimulating, anticonvulsant effect. Coriander sativum - contains essential oil, borneol, thymol, camphene, betapinene, citronellol, nerol. It is used as a means of correcting taste and smell. Amomum subulate - contains essential oils (a-terpineol, myrcine, limonin, sabinin, b-felladrin, borneol). Has a stimulating effect. Emblica officinalis – contains a large amount of vitamin C, vitamins B1, B2, trace elements, calcium, phosphorus, iron, pectin. Reduces blood cholesterol levels with pectin. The high content of biologically active, natural, easily digestible vitamin C causes an antioxidant effect. Stimulates erythropoiesis, protein biosynthesis, promotes proper reproduction of tissues of mesenchymal origin - bone dentin and collagen. INTELLAN acts as a neurohumoral transmission modifier and has a stimulating effect on the metabolism of the cerebral cortex, stimulates brain activity and memory development. INTELLAN improves blood circulation in the brain, increases the supply of nutrition to nerve cells, and removes metabolic products. The mild neurostimulating effect reduces anxiety and helps in the treatment of subacute depressive conditions. Indications for use - cerebrovascular accidents - attention and (or) memory disorders - decreased intellectual abilities - asthenic conditions (psychogenic or neurotic) - overstrain and fatigue - neurosensory disorders (dizziness, tinnitus) - delayed mental and physical development of children - subacute depression and increased anxiety. Directions for use and dosage Adults – 2 teaspoons, 2 times a day. Children from 3 to 15 years old – 1 teaspoon 2 times a day. The drug is taken after meals. Side effects - possible allergic reaction to the components of the drug - sleep disturbance if the drug is taken at night Contraindications - increased individual sensitivity to the components of the drug - diabetes mellitus - exudative diathesis Drug interactions Not identified Special instructions The syrup contains sucrose, which must be taken into account by patients with diabetes mellitus, exudative diathesis, as well as with a hypocaloric diet. Use during pregnancy and lactation is not recommended, since there are no clinical data on the use of the drug during this period. Overdose Not identified Release form and packaging Syrup 90 ml in dark glass bottles, in cardboard packaging. Storage conditions Store at a temperature not exceeding +25ºС. Keep out of the reach of children! Shelf life: 3 years Do not use after the expiration date indicated on the package. Conditions for dispensing from pharmacies Without a prescription Manufacturer Herbion Pakistan Pvt Ltd 75400, Pakistan, Karachi Korangi Industrial Area, 30/28
Indications for use
- chronic stressful situations , overexertion and fatigue;
- cerebrovascular accidents;
- attention disorders, memory loss, forgetfulness;
- decreased intellectual capabilities;
- neurosensory disorders;
- subacute depressive states (in the form of auxiliary treatment);
- increased anxiety ;
- astheno-neurotic conditions in somatic diseases .
Indications
It is worth paying attention to the fact that the drug has a number of contraindications and indications for use. For example, it is prescribed for circulatory disorders, as well as in cases of mental and memory disorders. Depressive conditions, a feeling of constant fatigue, as well as overstrain and neurosensory disorders - all these are direct indications for taking the drug.
"Intellan", the instructions, reviews and description of which are presented to your attention, is also prescribed for children. For example, with developmental delays. We are talking about both mental and physical condition. So, you should not be surprised if your child is suddenly prescribed this medication. In addition, it can also be taken as a vitamin complex “for the mind.”
Instructions for use of Intellan (Method and dosage)
Capsules and syrup are taken orally. Dose for adults - 1 capsule or 2 tsp. syrup 2 times a day after meals. In the evening, take capsules or syrup 3-4 hours before bedtime. Duration of treatment is from 1 to 3 months. The course can be repeated after a 3-week break.
Intellan syrup is preferable for children from 3 to 15 years old, it is prescribed 1 tsp. 2 times a day.
The instructions for use of Intellan contain a warning that the syrup contains sucrose , so it should not be taken by patients with diabetes .
Cost and side effects
Of course, we must not forget about such indicators as the cost of the medication, as well as side effects. They influence quite strongly what kind of reviews Intellan earns from consumers.
In this regard, all opinions can be divided into two categories. The first believes that this drug is not very expensive. And even side effects cannot make you stop taking it. For one package of medicine in Russia you will have to pay from 180 to 250 rubles. So it's really not very expensive.
The second category of doctors and buyers assures that despite the low cost, the side effects of the drug discourage use. Intellan earns negative reviews in this regard. After all, no one wants to develop a rash, itching, tachycardia, eternal fatigue syndrome, headaches and nausea after taking capsules or syrup. Not the best effects, but, nevertheless, they are not so dangerous for the health of modern people.
Analogs
Level 4 ATX code matches:
Ginos
Akatinol Memantine
Tanakan
Noodzheron
Ginkgo biloba
Bilobil
Memantine
Memoplant
Ginkum
Vitrum Memory
Namenda
There are no structural analogues. Preparations containing ginkgo biloba : Ginos , Bilobil , Memoplant , Tanakan , Gingium .
Reviews about Intellan
Analyzing reviews of Intellan, we can conclude that the drug is used not only to treat adults, but also children with functional and organic lesions of the central nervous system. It is prescribed to children, starting from 2 years of age, with psycho-speech-motor developmental delay. Taking the drug improved psycho-speech development: speech, auditory perception and cognitive activity of children improved. Fine motor skills have also improved.
There is no addiction to the drug, so it can be taken for a long time as prescribed by a doctor.
“I’m giving the child Intellan for the second year. The drug helps, the benefits for the child are tangible.”
“We took the course for 3 months. Very good results: my thinking has improved, I began to invent, compose and reflect a lot.”
“We are taking Intellan for the second time, a course of 2 months. We are pleased with the results."
“We’ve only been drinking for a week, but the child has perked up and is trying to repeat words.”
Many people note excessive excitability and sleep disturbance in adults and children if the drug is taken at night. In isolated cases, stool upset was observed after taking the drug.
When and under what conditions is Intellan prescribed?
In the stages of remission for any somatic diseases of an asthenic nature, doctors often prescribe Intellan. Reviews from patients in the treatment of psychogenic and neurotic syndromes also prove its high effectiveness. Therefore, in conditions such as increased anxiety, feelings of fear (especially at night), emotional instability, difficulties in establishing contacts with people, sleep disorders, Intellan is able to correct brain function, improving the well-being of patients.
The drug is effective for overexertion, fatigue, pre-depressive conditions, memory impairment and difficulty concentrating.
What else is interesting about the drug “Intellan”? Instructions for use, reviews from patients and doctors note its high effectiveness in cerebrovascular accidents, the symptoms of which are expressed by dizziness and tinnitus.
To increase the intellectual abilities of school-age children and students, as well as to maintain brain activity during exams, Intellan will be an indispensable assistant.
The drug does not cause drowsiness, but at the same time corrects sleep, making it deep and restful.
Intellan price, where to buy
You can buy it in many pharmacies in Moscow and other Russian cities. The price of Intellan in capsules No. 20 is 185 - 227 rubles. Intellan syrup is currently not available in the pharmacy chain.
- Online pharmacies in RussiaRussia
- Online pharmacies in KazakhstanKazakhstan
LuxPharma* special offer
- Intellan syrup bottle 120ml
RUR 1,880 order
ZdravCity
- Intellan capsules 20 pcs.Herbion Pakistan (PVT) Ltd
230 rub. order
- Intellan syrup 90mlHerbion Pakistan PVT Ltd
RUB 188 order
Pharmacy Dialogue
- Intellan capsules No. 20Herbion
RUB 203 order
show more
Reviews of people taking Intellan
According to doctors, as they describe patient reviews of the drug “Intellan”, this drug is very helpful in improving brain function. Many people whose work involves intellectual activity note a decline in moral strength when they are very busy. After a course of taking the drug, in most cases, positive changes in brain function were noted, intellectual abilities increased, and memory improved. The well-being of patients also improved; they coped with stress more easily and were more resistant to depression and nervous breakdowns.
