Which is better: Phenazepam or Diazepam


Content:

  1. Clonazepam: mechanism of action
  2. Physiological effects
  3. Pathological effects
  4. Addiction and withdrawal symptoms
  5. Overdose


Medicines are invented for a good purpose - for the treatment of various pathologies. But many of them also have negative properties, including the ability to cause drug addiction. Such drugs include clonazepam - the action of this drug is aimed at eliminating neurological and mental problems, but it also exhibits psychotropic properties.

Clonazepam: mechanism of action

The drug belongs to the benzodiazepines. It acts on GABA (gamma-aminobutyric acid) receptors. At the same time, the release of neurotransmitters that provoke excitation of nerve cells is blocked - as a result, processes that are too actively occurring in them are inhibited.

The substance is quickly absorbed into the bloodstream from the lumen of the small intestine. Its greatest amount in the blood is detected after 2-3 hours, at which time the most pronounced effect appears. Such a quick effect was appreciated not only by clinicians, but also by drug addicts - the medicine is used to relieve anxiety that develops when using a number of psychotropic substances.

The effect of the drug increases if it is used together with:


  • barbiturates;
  • opiates;
  • alcoholic drinks;
  • some antidepressants;
  • desensitizing.

Comparison of the safety of Phenazepam and Diazepam

The safety of a drug includes many factors.

At the same time, for Phenazepam it is quite similar to Diazepam. It is important where the drug is metabolized: drugs are excreted from the body either unchanged or in the form of products of their biochemical transformations. Metabolism occurs spontaneously, but most often involves major organs such as the liver, kidneys, lungs, skin, brain and others. When assessing the metabolism of Phenazepam, as well as Diazepam, we look at which organ is the metabolizing organ and how critical the effect on it is.

The risk-benefit ratio is when the prescription of a drug is undesirable, but justified under certain conditions and circumstances, with the obligatory observance of caution in use. At the same time, Phenazepam does not have any risks when used, just like Diazepam.

Also, when calculating safety, it is taken into account whether only allergic reactions occur or possible dysfunction of the main organs. In other matters, as well as the reversibility of the consequences of using Phenazepam and Diazepam.

Physiological effects

When using this medicine, anxiety, fear and restlessness are relieved. Therefore, indications for its use are pathologies in which the following occur:

  • psychomotor agitation;
  • anxiety and panic attacks;
  • epilepsy attacks;
  • febrile convulsions - those that appear when body temperature rises (usually this is observed when its values ​​are above 38 degrees Celsius);
  • hypertonicity is muscle tension that can occur in a number of pathologies of the nervous and musculoskeletal systems.

Please note: The medicine has also been identified to have some other properties. Thus, under its influence, the slow-wave sleep phase becomes longer, and the fast sleep phase becomes shorter. But clonazepam is not used as a sleeping pill because it takes a long time to be eliminated from the body.

About Phenazepam

The medicine is a highly effective tranquilizer, which has an advantage over its analogues - a complex effect on the body as a whole.

Indications for use

  • insomnia, sleep disorder
  • unreasonable feelings of fear, anxiety and restlessness
  • panic attacks
  • seizures, nervous tics
  • post-traumatic shock
  • neuroses, psychoses
  • depression
  • emotional instability
  • attacks of aggression
  • epileptic seizures

Pathological effects

They develop not only when taking higher dosages or using them for a long time. Patients complain that during therapy with this drug they experienced:


  • feeling of mental and physical fatigue (even when performing normal amounts of work);
  • constant drowsiness;
  • difficulty trying to concentrate;
  • amnesia - forgetfulness;
  • “lubrication” of emotions;
  • euphoria is what drug addicts take this drug for.

When taking clonazepam, the action time is 12 hours. The body quickly develops tolerance to it - it becomes insensitive in just a few weeks. Addicts are forced to take it in larger doses to produce a “high” effect.

A number of somatic disorders also develop. Many experienced disorders of the gastrointestinal tract - increased appetite, dry mouth, nausea, diarrhea. A number of patients experienced incoordination of movements, dizziness, and muscle weakness. Despite the fact that clonazepam relieves psychomotor agitation, it can also have the opposite effect - provoke increased motor activity.

But most of all, clonazepam is dangerous for the functioning of the cardiovascular and respiratory systems - it depresses breathing and provokes a decrease in blood pressure. Taking it for diseases of the blood vessels, heart and lungs can lead to significant disturbances in the functioning of these organs. If a person who has been diagnosed with such pathologies has just started using drugs and has not yet lost control of himself, he should first of all give up this drug.

When using clonazepam for narcotic purposes, the following occurs quite quickly:


  • increased excitability;
  • irritability;
  • a feeling that something bad is about to happen;
  • aggressiveness;
  • panic attacks;
  • insomnia;
  • nightmares at night.

Comparing tranquilizers

If we compare Phenazepam and Clonazepam, then the first drug will be stronger in its effect than the second, since the permissible daily dose of the drug per day is 10 mg, and Clonazepam is as much as 20 mg. Both drugs affect the nervous system, inhibiting its functions . Therefore, long-term treatment with these tranquilizers is not recommended, as drug dependence may develop. Dependence manifests itself in the fact that it seems to you that the previous dose is no longer effective and you begin to increase it on your own. This can lead to an overdose with very bad consequences. But still, dependence on Phenazepam is observed much more often than on Clonazepam.

Unlike Clonazepam and Phenazepam, the first drug is used mainly to treat problems associated with convulsions and epileptic seizures, taking into account the effectiveness of the muscle relaxant effect. But this does not mean that Clonazepam helps only with this - it has the same actions as other drugs in the benzodiazepine group.

Another advantage of Clonazepam is that the drug acts quickly and for a short time. This means that the medicine is not as toxic as Phenazepam.

Clonazepam should not be taken together with Phenazepam, since mixing tranquilizers with each other can lead to an overdose. It is also prohibited to use these drugs together with alcohol or drugs, as they mutually enhance each other’s effects, negatively affecting the central nervous system. This threatens severe poisoning, which can lead to coma and even death.

Both medications are contraindicated in pregnant women and women during lactation.

But what is still stronger: Phenazepam or Clonazepam? The answer is Phenazepam. It is a very serious remedy. Another fact that indicates the extreme effectiveness of the drug is that Clonazepam can be taken by children for medicinal purposes, while Phenazepam cannot. But still, due to the fact that these are psychotropic drugs, they are dispensed in pharmacies only with a special prescription from a doctor.

You also need to stop taking these tranquilizers gradually and under the supervision of a doctor, because the so-called withdrawal syndrome may develop, and this is a very painful process for the body.

Addiction and withdrawal symptoms

Clonazepam is dangerous not only because of the symptoms described - side effects also manifest themselves in the form of addiction. It happens:

  • mental - a lover of “expanding consciousness” does not want to give up this psychotropic because he wants to be in a state of euphoria;
  • physical - organs and tissues are no longer able to function normally if the drug does not enter the body.

With a sharp cessation of use, abstinence develops (syndrome o). There are:


  • insomnia - it is difficult for an addict to fall asleep, he easily awakens under the influence of even unexpressed stimuli (light, sound, tactile);
  • pain throughout the body;
  • restlessness to the point of throwing;
  • psycho-emotional leaps;
  • nervousness;
  • hot temper.

Suicidal intentions may also appear. In addition, the addict begins to feel that the world is “somehow different” - the usual perception of people, events, phenomena, and objects is disrupted. In severe forms of withdrawal, seizures and psychotic reactions may occur, as when abruptly quitting alcohol.

You can overcome addiction by

The Narconon program is an integrated, comprehensive approach that allows a person to get out of the trap. This technique differs from all others in that here a person does not resist cravings, does not fight addiction, but directs his attention and energy to creation, new skills, knowledge and improvement in all areas of life.

A person regains his best qualities and abilities, and as a result, ceases to need artificial methods (drugs) to improve his condition.

If you are facing a drug addiction problem, call us right now!

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Overdose

Since this drug is addictive, the addict takes it in larger quantities - an overdose occurs. In comparison with the same phenomenon when using a number of drugs, its symptoms are not critical. It usually manifests itself as memory impairment.

With an overdose, internal barriers disappear. This is manifested by swagger in behavior - a person can do or say something that he has not done or said before. Lethal outcome is almost impossible, but there are other warnings. Under the influence of clonazepam in high doses, concentration and the ability to control events around them sharply deteriorate, because of this there is a risk of an accident - a drug addict can get run over by a car, fall from a height, and so on.

Literature:

  1. Clonazepam: indications, side effects and possible non-medical uses. / Dokkedal-Silva V., Berro L.F., Galduroz J.K.F., Toufic S., Andersen M.L. / Harv Rev Psychiatry. 2019 September/October; 27 (5): 279-289. DOI: 10.1097/HRP.0000000000000227. / PMID: 31385811.
  2. Issues of clinical use of benzodiazepines: effectiveness, withdrawal syndrome / Chouinard J. / J Clin Psychiatry. 2004; 65 Supplement 5: 7-12. / PMID: 15078112.
  3. Barbiturates, benzodiazepines, anabolic steroids: history of creation, action, analysis: educational and reference manual / M. Yu. Zakharchenko, I. N. Melnikov, D. V. Kairgaliev; edited by S. Ya. Pichkhidze. - Saratov: KUBiK, 2015. - 189 p.
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