Action of phenibut
It has several different effects on the nervous system and mental state:
- Reducing anxiety and fear.
- Normalization of sleep, making it easier to fall asleep.
- Nootropic effect: by improving the metabolism of nerve cells, attention, memory and reaction speed are improved.
- Relieves symptoms of dizziness, stuttering, enuresis and tics in children.
- Anticonvulsant action.
- Analgesic effect.
- Improves endurance.
The mechanism of action is complex and is associated with a direct effect on GABA receptors, which leads to increased inhibition processes caused by gamma-aminobutyric acid.
Also, by improving blood microcirculation in the small vessels of the brain and reducing the processes of lipid peroxidation, it helps restore normal metabolism of nerve cells (neurons). Thus, it combines the effect of a tranquilizer (sedative) and a nootropic-vascular drug.
Drug substitutes for children
There are generics of Phenibut on the pharmacological market, which are often used in the treatment of children.
Noofen
Noofen is a nootropic medication that is prescribed as a psychostimulant. The main component of the medicine is phenibut.
The drug has the following properties:
- tranquilizing and stimulating neuronal activity;
- antihypoxic and antiamnestic.
Characteristics of the drug
The medication also improves the child’s intellectual ability, improves his performance, relieves mental stress and eliminates fears and anxiety.
Noofen is effectively used in the treatment of such pathologies:
- emotional overexcitation;
- decreased memory and attentiveness;
- low intellectual development;
- asthenic and neurotic anxiety state;
- neuroses;
- psychopathy;
- anxiety, causeless worry and a feeling of fear;
- childhood enuresis and stuttering;
- insomnia in old age;
- alcohol syndrome;
- dysfunction of the vestibular apparatus
- climacteric disorders in women.
Psychopathy
It is prohibited to prescribe Noofen for the following reasons:
- kidney failure;
- hypersensitivity to the composition of the drug;
- children under 8 years old;
- lactation period.
The drug can be used as part of a combination treatment with tranquilizers and antipsychotics. Adults are prescribed a dosage of 250-500 mg per day, maximum 750 mg. Children over 8 years old – no more than 500 mg per day. Therapeutic treatment continues for 3-6 weeks.
Negative effects occur infrequently in patients and are manifested by the following symptoms:
- urticaria and anaphylactic reactions;
- respiratory tract pathologies – laryngeal edema;
- dyspepsia;
- headache.
Noobut
Noobut is a generic version of Phenibut with the active ingredient - phenibut. The drug belongs to the pharmacological group of nootropic medications. In terms of its properties, Noobut is identical to Noofen and Phenibut, and also has the same purposes as them:
- decreased quality of sleep – insomnia;
- to increase emotional and intellectual activity;
- decreased memory and attention;
- a state of anxiety, causeless anxiety and fear;
- childhood nervous pathologies - tics, stuttering and nocturnal enuresis;
- problem of falling asleep in elderly patients.
The drug is also prescribed as part of the complex treatment of cervical osteochondrosis. Noobut is used as part of preventive measures for seasickness or motion sickness in transport, for vestibular disorders.
Osteochondrosis of the cervical spine
Noobut should not be prescribed to children under 3 years of age, as well as in cases of renal failure and allergies to the ingredients in the medication. During lactation, it is necessary to transfer the newborn to artificial feeding, and only then begin therapy. For pregnant women, medication can only be prescribed by a doctor based on vital signs.
For adult patients and children older than 11 years, these dosages are 250-500 mg three times a day. Children's dosages depend on the age of the children:
- 3-4 years – 2 times a day, 0.1 mg;
- 5-6 years – three times 0.1 mg;
- 7-11 years - twice 0.2 mg.
The duration of taking the tablets is 21-45 days. Preventive measures for motion sickness - take 250-500 mg of medication an hour before the trip. To relieve alcohol syndrome, the initial dosage is 750 mg, followed by a decrease. Side effects of Noobut are identical to those of Noofen.
Lutsetam
Lucetam is produced in tablets and in a solution for injections based on piracetam. A Phenibut substitute is prescribed for the treatment of the following diseases:
- psychoorganic syndrome;
- disorders and behavioral disorders;
- decreased concentration and memory;
- deviations in movement coordination;
- emotional overexcitation;
- dementia and Alzheimer's disease;
- dizziness;
- alcohol syndrome;
- myoclonus of cortical etiology;
- poor learning ability of schoolchildren;
- post-traumatic period (head and brain injury).
Psychoorganic syndrome
Also prescribed after an ischemic stroke to restore the functioning of the motor and speech apparatus, as well as enhance mental and emotional activity.
Lutsetam is not prescribed under the following circumstances:
- hemorrhagic stroke;
- allergy to medicinal components in the medicine;
- kidney failure;
- breastfeeding a newborn;
- the entire period of pregnancy.
Tablets should be taken with meals - 2-4 times a day. To prevent sleep rhythm disturbances, the last intake procedure should be no later than 5 pm.
When treating intellectual disabilities, the medication is taken 2-3 times a day. Dosage per day – 2400-4800 mg. For cortical disorders - the initial dosage in therapy is 7200 mg, and there is a gradual increase by 4800 mg every 3 days until a maximum dosage of 24000 mg is reached. After achieving a therapeutic effect, it is necessary to gradually reduce the dosage by 1200 mg every 2 days.
Negative effects from taking Lucetam:
- headaches, fluctuations in blood pressure index and dizziness;
- insomnia or drowsiness;
- dyspepsia;
- epileptic seizures and impaired coordination;
- irritability and nervousness;
- weight gain;
- increased libido;
- hallucinations, depression.
Indications for use
Phenibut is prescribed for both disease and non-painful conditions.
- Stress, overwork, lack of sleep, preparation for physical and mental stress and operations.
- Asthenia (asthenic syndrome, neurasthenia, VSD, astheno-neurotic state).
- Tension headache.
- Anxiety disorders: panic attacks, generalized anxiety disorder, phobias (fears).
- Neuroses, neurosis-like states.
- Personality disorders.
- Consequences of organic damage to the nervous system.
- Withdrawal state due to alcohol, drug addiction, smoking.
- Dizziness, Meniere's disease, motion sickness.
- Insomnia.
- Psychosomatic diseases.
- In children: stuttering, tics, enuresis, aggressiveness, developmental delay.
A prerequisite for taking phenibut is a doctor's prescription. Self-use is prohibited!
Similar remedies in other forms
Similar drugs Phenibut can be produced in several dosage forms - tablets, oral or injectable solutions.
Nootropil
Nootropil is produced in a solution for drip administration, capsules, a solution for injections and tablets. Nootropil contains piracetam, which provides the drug with nootropic properties.
Effect of the drug
The medication is prescribed in the following cases:
- coma of toxic or post-traumatic etiology;
- a sharp decrease in memory quality;
- severe dizziness;
- unsteadiness of gait and disturbances in coordination of movement;
- decreased attention and intellectual abilities;
- Alzheimer's disease;
- alcohol dependence in the chronic stage;
- sickle cell anemia;
- myoclonus of cortical type;
- condition after ischemic stroke.
Nootropil is not used in patients with kidney dysfunction, with hypersensitivity to the composition, as well as during lactation and children under 12 months. It is strictly forbidden to use after a cerebral hemorrhage.
Nootropil is prescribed with great caution during pregnancy.
The daily dosage of Nootropil is divided into 2-3 doses:
- psychoorganic disorders – 2400-4800 mg;
- treatment of dizziness – 2400-4800 mg;
- myoclonus - initial dosage 7200 mg and every 2-3 days increase by 4800 mg until reaching 24000 mg;
- dyslexia in a child older than 8 years – 3200 mg per day.
Adverse reactions:
- hallucinations and asthenia;
- increased irritability and overexcitement;
- manifestation of epilepsy;
- depression;
- drowsiness and lethargy;
- dyspepsia;
- skin allergies.
Cavinton
Cavinton is a vasodilator of cerebrovascular pathologies. The drug is an analogue of Phenibut based on vinpocetine and restores human brain activity. Cavinton improves the flow of blood into the cerebral arteries, which increases the delivery of oxygen to neurons.
The medication does not affect myocardial activity or blood pressure. The drug is prescribed for the treatment of the following cerebral disorders:
- memory loss and a sharp decrease in intellectual abilities;
- transient ischemic attacks;
- encephalopathy;
- cephalgia;
- tinnitus.
Properties of the drug and dosage
The drug is not prescribed to patients with the following concomitant pathologies:
- cardiac arrhythmia;
- unstable pressure index;
- severe kidney pathologies;
- lactation and pregnancy.
For treatment, 1-2 tablets are prescribed three times a day. For maintenance treatment – 1 tablet also 3 times a day. The first therapeutic effect can be felt 7-14 days after the start of treatment. The solution is administered only using a dropper - 1 ampoule per 0.5 liter of sodium chloride once a day, and in case of severe pathologies the frequency of procedures is increased up to 3 times.
For children, the medication is administered by drip – Cavinton is diluted in a glucose solution. Therapeutic treatment lasts 2-3 weeks, and after intravenous treatment the patient is transferred to taking tablets.
Negative actions of Cavinton:
- arrhythmia and blood pressure fluctuations;
- dizziness and severe pain in the head in different locations;
- increased body fatigue;
- dyspepsia;
- skin allergy.
Cortexin
Cortexin is a nootropic with cerebroprotective effects and anticonvulsant effect based on Cortexin.
The medication is used in the treatment of such pathologies:
- viral neuroinfection;
- insufficiency of cerebral blood flow;
- transient ischemic attacks;
- brain injury;
- encephalopathy and encephalomyelitis;
- cerebral ischemia;
- asthenic syndrome;
- epilepsy;
- encephalitis;
- Cerebral palsy and developmental disorders in children;
- decreased memory and intelligence;
- autonomic disorders;
- delayed development of the child’s speech apparatus.
Properties of Cortexin
It is not recommended to take Cortexin during pregnancy and lactation, as well as if you are allergic to the components of the medication.
Cortexin solution is administered intramuscularly every day once a day for 10-15 days. The solution is diluted with sodium chloride or lidocaine (procaine). The daily permissible dosage for an adult is 10 mg, and for children weighing less than 20 kg - 0.5 mg per kilogram of the child’s weight. After six months, the course of treatment can be repeated.
For the treatment of stroke, 10 mg of Cortexin must be administered twice a day for 10 days. If necessary, the course is repeated.
Adverse reactions to Cortexin are quite rare, and patients report allergic reactions on the skin in the form of rash, hives, itching and redness at the injection site.
Phenibut addiction
With prolonged, uncontrolled use of phenibut, mental and physical dependence may develop. This may require special treatment from a psychiatrist-narcologist and subsequent rehabilitation. As a rule, cases of dependence on phenibut were observed in persons dependent on psychoactive substances who had a long history of drug addiction and who switched from using the drug to phenibut. The development of primary dependence on phenibut only after long-term use is extremely rare.
Cost of medicines and basic analogues
The cost of Phenibut is in the high price segment, as well as its foreign analogues and generics. Domestic similar medications of Phenibut are much cheaper.
Name of the drug and its analogues | Dosage of the main component (mg) | Quantity in 1 package | Cost in rubles |
Phenibut | 250 | 20 | 972-1000 |
Afobazole | 10 | 60 | 532-550 |
Omaron | 25+400 | 60 | 336-400 |
Glycine | 100 300 | 50 20 | 181-200 171-198 |
Noofen | 250 | 20 | 2996-3000 |
Noobut | 250 | 20 | 470-530 |
Lutsetam | 400 800 1200 | 60 30 20 | 441-500 568-600 684-710 |
Ceraxon solution | 1000 1000 | 20 5 ampoules of 4 ml | 3357-3364 1830-1900 |
Anvifen | 250 | 20 | 378-400 |
Biotropil | 1200 | 20 | 549-600 |
Nootropil solution | 800 1200 20% | 30 20 12/5 ml | 364-400 523-550 729-740 |
Cavinton solution | 5 10 10 | 50 20 10/2 ml | 1029-1045 1224-1250 1311-1320 |
Cortexin | solution | 10 | 1625-1670 |
Introduction
Phenibut is a nootropic drug whose main active substance is aminophenylbutyric acid. It is an anti-anxiety agent, reduces anxiety, fear, improves sleep, increases brain activity and memory. It is fast-acting and has a long-lasting effect. In most cases, Phenibut is sold as prescribed by a doctor.
Phenibut from SNS Smart Powders can be purchased without a prescription in sports nutrition stores. The drug is a dietary supplement and is available in dosages of 300 and 500 mg.
Fig 1 - Phenibut SNS Smart Powders
Let's figure out what can be replaced?
Analogues of the drug are products in which the main active substance is aminophenylbutyric acid. Substitutes are nootropic drugs that have similar pharmacological effects and similar indications for use.
Some medications are sold only with a doctor's prescription, but there are also over-the-counter analogues. The products are presented in various forms of release - tablets, capsules, powders. In Russia, drugs are not prohibited.
Over-the-counter analogues
Nootropil
This is an over-the-counter nootropic. Stimulates brain function, thinking, memory, attention. The active substance is piracetam.
What's better? Since Phenibut’s anti-anxiety effect is higher than its nootropic effect, it is recommended to choose this drug in the following cases:
- anxiety and depression;
- for sleep disorders;
- dizziness, motion sickness;
- nervous tics;
- stuttering in children;
- vegetative-vascular dystonia;
- agitation or aggression during withdrawal from substances containing alcohol.
Afobazole
Also refers to anti-anxiety drugs, the main component of which is fabomotizole. This antipsychotic is prescribed:
- with emotional instability;
- for anxiety conditions;
- with asthenic syndrome (alcohol or drug);
- for somatic diseases (ischemia or myocardial infarction, asthma, lupus erythematosus), oncological tumors.
What's better? Although the effect of administration is similar, the drugs are not analogues; they have different compositions and active substances. The effect of Afobazole is milder and is sold without a prescription. According to patient reviews, it is noted that Phenibut is more effective.
Picamilon
This is a nootropic drug, with aminobutyric acid, but in different proportions. It is prescribed for decreased mental activity, vascular diseases, dizziness and headaches.
Let's try to compare drugs: which is better, Phenibut or Picamilon? Both improve brain function and are sedative. The difference is in the action of these drugs. For anxiety, worries, stress, and insomnia, the first drug is more effective. It is also more popular and more widely used.
Piracetam
This over-the-counter nootropic dilates blood vessels in the brain, improves cerebral circulation and brain health, and also has an antioxidant, antiplatelet, psychostimulant, anti-migraine and tranquilizing effect.
What's better? Both drugs improve memory and thought processes, but there are differences. Phenibut is more effective in treating anxiety conditions.
Prescription analogues
Anvifen
According to reviews, it is an analogue of Phenibut, a nootropic agent containing aminophenylbutyric acid. The drug also has antiplatelet, tranquilizing, antioxidant and anticonvulsant properties. Applicable in case:
- anxious, neurotic state;
- irritability, anxiety, sleep disturbances;
- to improve memory and attention;
- for motion sickness and dizziness.
The difference between Anfiven is the release form - the product is available in capsules of 25 mg, 50 mg, 125 mg and 250 mg.
Which is better Anvifen or Phenibut? The drugs have only one active ingredient. The difference is in the release form - the choice of capsules of different dosages from the analogue allows you to take the dose of the medicine more accurately. At the same time, according to patient reviews, Phenibut is a more effective, time-tested drug.
Noofen
The next analogue of Phenibut is Noofen. The composition contains the main component - aminophenylbutyric acid, available in capsules, tablets, and powder. Produced only in Latvia.
Both products have similar effects. What is the difference between the drugs? The difference between drugs is in the composition of excipients, as well as in the quality of raw materials and the production process. The quality of raw materials for the production of Phenibut is much better, and in addition, the drug is cheaper in terms of the number of capsules and active ingredient.
Phenazepam
The anti-anxiety drug is an anxiolytic, has an inhibitory effect on the structures of the brain and nervous system, relaxes muscles, and gives a hypnotic effect.
What is the difference? Which remedy is better Phenibut or Phenazepam? The drugs differ in composition and mechanism of action.
The second is stronger, but causes addiction; in case of an overdose, it leads to a state close to the symptoms when taking narcotic drugs. It has many side effects and more contraindications.
It can be purchased only as prescribed by a doctor, and it is prohibited in childhood.
Grandaxin
Just like Phenibut, it has an anti-anxiety effect. This is a tranquilizer containing a benzodiazepine. It is used for:
- nervous system disorders, anxiety;
- moderate depression;
- withdrawal symptoms after alcohol/drugs.
What is better Phenibut or Grandaxin? Both drugs have an anxiolytic effect - they reduce anxiety and emotional stress. Moreover, these drugs have different compositions. The second drug is more narrowly targeted, it has more contraindications and side effects, it causes excitement, and according to reviews, the positive effect comes more slowly.
Atarax
This drug belongs to the group of anxiolytics and is used:
- with increased irritability and nervousness;
- to reduce feelings of fear, panic attacks;
- for alcohol syndromes;
- for itching.
What's better? The drugs have different effects. Atarax is a sedative. Phenibut has a stronger and broader effect, it copes with insomnia, increases concentration and attention. According to patient reviews, it is better as a sedative and nootropic than its analogue.
Fenotropil
This is a drug belonging to the group of nootropic drugs. The active substance of the nootropic has the same name – phenotropil. This medicine is used for:
- diseases of the central nervous system;
- increased loads;
- deterioration of memory and attention.
What's better? The effects of the drugs are similar. But if you compare them, you can see the difference in composition, active ingredient and indications for use. For anxiety disorder, neurosis, and disrupted sleep cycle, Phenibut will be more effective. Phenotropil is better for mental work.
Adaptol
This anxiolytic drug, which stimulates the production of serotonin, is used for neuroses, heart pain not associated with ischemia, menopause, and in the treatment of nicotine and alcohol addiction. Produced only in Latvia.
These medications have different compositions and different effects on the body. The first has a wider scope of application and has a stronger effect on the human body. According to doctors, it eliminates symptoms of nervous disorders better and faster. It is also better to choose Phenibut for treating a child than its analogue.
Teraligen
This antipsychotic is used for:
- anxiety, phobias, feelings of fear, panic;
- excitability and imbalance, hysteria;
- for allergic reactions.
Phenibut and Teraligen give a similar effect, but differ in their pharmacological group. The second drug has a narrower sphere of influence, but its effect on the body is stronger, and there are more side effects and contraindications. The first one is much better due to its milder effect on the body and minimal side effects.
When choosing between Phenibut and its analogues, we recommend basing it on the indications for use, contraindications, doctor’s recommendations for your disease, the quality of production and raw materials for the manufacture of the medicine and the effectiveness of the action.
Phenibut is an effective anti-anxiety and nootropic drug. If patients follow the recommendations of the attending physician, the instructions for the method and dose of use, the result is a quick, effective and lasting long-lasting effect.
conclusions
The drug Phenibut is time-tested and is one of the best for overcoming anxiety and depression. Reviews from patients indicate significant improvements when taken.
Where to buy without a prescription?
- You can order the drug without a prescription on our website using the link:
- This drug belongs to sports nutrition and does not require a doctor’s prescription.
- Register on our website and receive a discount on your first order using coupon: FENANAL.
Phenibut or Phenazepam - which is better and stronger, what is the difference
Manufacturer: Valenta, Russia
Release form: ampoules, tablets
Active ingredient: benzodiazepine
Synonyms: Phenazef, Phenazeptin, Elzepam
Phenazepam is a strong tranquilizer that is available from pharmacies only with a prescription. Causes addiction when used for a long time. It has strong hypnotic, sedative, anticonvulsant, muscle relaxant and anxiolytic effects.
This analogue is approved for use only under strict control of dosage and duration of administration.