Comparison of the effectiveness of Ceraxon and Cerebrolysin
Ceraxon is more effective than Cerebrolysin - this means that the ability of the drug substance to provide the maximum possible effect is different.
For example, if the therapeutic effect of Ceraxon is more pronounced, then it is impossible to achieve this effect with Cerebrolysin, even in large doses.
Also, the speed of therapy is an indicator of the speed of therapeutic action; Ceraxon and Cerebrolysin are also different, as is bioavailability - the amount of a drug substance reaching the site of its action in the body. The higher the bioavailability, the less it will be lost during absorption and use by the body.
Cerebrolysin
A drug that has nootropic and neurometabolic effects . Improves metabolism in brain cells, prevents their death during ischemia and hypoxia. Enhances intracellular protein synthesis in the brain.
It has a positive effect on cognitive impairment, improves attention and memory, and helps regulate behavior.
Has a moderate antioxidant effect .
Active ingredient: Cerebrolysin concentrate (a peptide complex obtained from pig brain cells).
Release form: solution for injection. Intended for intramuscular and intravenous administration.
Cerebrolysin as an active component contains a complex of neuropeptides that are obtained from the brain of pigs.
The active substance penetrates directly through the BBB to the nerve cells of the brain and has the following effects:
- Improves metabolism in the central nervous system and protein biosynthesis in the brain of children and the elderly.
- Protects nerve cells from damage by lactic acid, prevents the formation of free radicals and neuronal death due to oxygen starvation and ischemia, and reduces their damage by glutamate.
- The drug improves cognitive function and memory.
Indications for use:
- Ischemic stroke.
- TBI and spinal cord injuries.
- Alzheimer's disease.
- Dementia of various etiologies.
- Chronic cerebrovascular insufficiency.
- Mental retardation in children.
- Attention deficit hyperactivity disorder.
- Forms of depression resistant to antidepressants (as part of complex therapy).
Do not use in case of individual intolerance to the components, acute renal failure, epilepsy. It can be taken during pregnancy provided that the benefit of the drug is greater than the risk of side effects in the fetus.
Produced in Austria. Dispensed by prescription.
Comparison of the safety of Ceraxon and Cerebrolysin
The safety of a drug includes many factors.
At the same time, in Ceraxon it is quite similar to Cerebrolysin. It is important where the drug is metabolized: drugs are excreted from the body either unchanged or in the form of products of their biochemical transformations. Metabolism occurs spontaneously, but most often involves major organs such as the liver, kidneys, lungs, skin, brain and others. When assessing the metabolism of Ceraxon, as well as Cerebrolysin, we look at which organ is the metabolizing organ and how critical the effect on it is.
The risk-benefit ratio is when the prescription of a drug is undesirable, but justified under certain conditions and circumstances, with the obligatory observance of caution in use. At the same time, Ceraxon does not have any risks when used, just like Cerebrolysin.
Also, when calculating safety, it is taken into account whether only allergic reactions occur or possible dysfunction of the main organs. In other matters, as well as the reversibility of the consequences of using Ceraxon and Cerebrolysin.
Cerakson
A nootropic drug intended for the treatment of sensory and motor neurological disorders of a degenerative and vascular nature. Prevents the death of brain cells and promotes the regeneration of damaged cell membranes. Inhibits the action of phospholipase.
In case of stroke, it reduces the volume of affected brain tissue and improves the transmission of impulses. In case of traumatic brain injury, it reduces the duration of coma and the recovery period.
Helps treat cognitive disorders such as loss of memory and attention, deterioration of speech and difficulties in performing habitual activities.
Has a moderate antioxidant effect .
Active ingredient: citicoline .
Release form: solution for intramuscular and intravenous administration, solution for oral administration.
Ceraxon contains citicoline as an active component, which has a wide spectrum of action:
- Participates in the process of restoration of damaged cell membranes.
- Blocks the appearance of free radicals and prevents cell death.
- Suppresses the action of phospholipases, which can negatively affect mucous membranes.
- With the development of a stroke, it reduces the degree of damage to brain tissue and improves the transmission of excitation in cholinergic synapses.
- In patients with traumatic brain injury, treatment with the drug reduces the duration of post-traumatic coma and recovery period, and makes neurological symptoms less pronounced.
- In case of chronic oxygen starvation, due to nootropic therapy, attention and self-care skills improve, and signs of amnesia are weakened.
Indications for use:
- Acute period after ischemic stroke (as part of complex therapy).
- Recovery period after ischemic and hemorrhagic stroke.
- Traumatic brain injuries and the recovery period after them.
- Behavioral and cognitive dysfunctions in brain lesions.
Cannot be used in case of individual intolerance to components, severe vagotonia, fructose intolerance, or under the age of 18 years. During pregnancy, it can be taken according to strict indications and provided that the benefit of the drug for the mother is higher than the risk of side effects in the fetus.
Made in Italy. Dispensed by prescription.
Comparison of addiction between Ceraxon and Cerebrolysin
Like safety, addiction also involves many factors that must be considered when evaluating a drug.
So, the totality of the values of such parameters as “o syndrome” in Cerakson is quite similar to the similar values in Cerebrolysin. Withdrawal syndrome is a pathological condition that occurs after the cessation of intake of addictive or dependent substances into the body. And resistance is understood as initial immunity to a drug; in this it differs from addiction, when immunity to a drug develops over a certain period of time. The presence of resistance can only be stated if an attempt has been made to increase the dose of the drug to the maximum possible. At the same time, in Cerakson the values of the “syndrome” are quite small, however, the same as in Cerebrolysin.
pharmachologic effect
Pharmacologically, both Mexidol and Neurox are drugs with the active ingredient – ethylmethylhydroxypyridinosuccinate. It has an antioxidant, metabolic and vasoactive agent, and it can also improve the metabolism of brain cells, the rheological properties of blood, and microcirculation processes. Also, ethylmethylhydroxypyridinosuccinate neutralizes the negative effects of a number of drugs, ethyl alcohol, and can improve the anticonvulsant effect of carbamazepines and the antiparkinsonian effects of levodopa drugs. The active ingredients of Mexidol and Neurox are similar.
Comparison of side effects of Ceraxon and Cerebrolysin
Side effects or adverse events are any adverse medical event that occurs in a subject after administration of a drug.
Ceraxon's side effects are almost the same as Cerebrolysin's. They both have few side effects. This implies that the frequency of their occurrence is low, that is, the indicator of how many cases of an undesirable effect of treatment are possible and registered is low. The undesirable effect on the body, the strength of influence and the toxic effect of Ceraxon are similar to Cerebrolysin: how quickly the body recovers after taking it and whether it recovers at all.
What do they have in common?
Ceraxon and Cerebrolysin have an antioxidant effect, improve the memory process and increase concentration. In addition, the drugs have the following similarities:
- Available in the form of a solution for injection into a muscle or vein.
- Contraindicated in case of individual intolerance to their composition, in which case the medications can cause allergies.
- Nootropic drugs can be used during pregnancy if the benefit to the mother exceeds the potential harm to the fetus.
- Both medications are used for ischemic stroke, traumatic brain injury, and senile dementia of various origins.
- Both nootropics can cause stomach upset, nausea, vomiting, lack of appetite, trembling of certain parts of the body, insomnia, changes in blood pressure, dizziness, headaches, and dyspnea.
- Cerebrolysin and Ceraxon have low toxicity and no cases of overdose with these medications have been reported.
Efficiency
The positive effect of using Neurox is confirmed by reviews of doctors and patients who have used it for various diseases.
Reviews from doctors
Experts say that Neurox is a good antioxidant, anticonvulsant and antihypoxic drug, but in most cases it is better to use it as an adjuvant remedy, in combination with drugs from other groups:
Patient reviews
Patients' opinions about Neurox are extremely positive: it helps normalize sleep, improve blood flow to the brain and get rid of headaches and manifestations of dystonia:
Anastasia: “To quickly recover after a heart attack and improve blood circulation in the brain, I was prescribed Neurox. According to the doctor, it is the lack of oxygen in the brain tissue that causes headaches and malfunctions in other organs and systems.
The fact that I would have to give injections did not upset me. They are known to work faster than pills. The drug not only normalizes blood flow in the brain, but also has a positive effect on heart tissue. The treatment lasted about a month. The only side effect was dry mouth. I am satisfied with the results of the therapy: my health has improved significantly.”
Neurox has a wide spectrum of action. Therefore, it is used in neurology, cardiology and other areas of medicine. The effectiveness of the drug has been confirmed by numerous studies and reviews. But a positive result from treatment can only be achieved if the product is used correctly and all recommendations of the attending physician are followed.
Dosage and release forms
The drugs differ in release forms. Mexidol is available both in the form of ampoules (injections) and in the form of tablets for oral administration; Neurox only has the form of a solution for injection. The Mexidol package contains 30 or 50 tablets (125 mg dose), and there is also a packaging of ampoules of 2 ml No. 10 and No. 50 (produced primarily for hospitals), 5 ml No. 5 and No. 20, for each ml of solution there is 50 mg active substance. Neurox has available packages of ampoules 2 ml No. 10, No. 50, 5 ml No. 5. In terms of release forms, Mexidol wins, since it is often desirable to consolidate the course of injections with a tablet form of the drug, while Neurox does not have this option.
Possible consequences and precautions
Negative consequences usually do not occur during Neurox therapy. But sometimes after its use the following symptoms occur:
fever, feeling of warmth in the body;
If at least one of the above symptoms appears, you should consult a doctor. He will adjust the dosage of Neurox or prescribe another drug.
Overdose of the drug is possible with prolonged use or administration of large doses. Its main features:
- constant drowsiness;
- difficulty falling asleep;
- increased blood pressure (slight).
As a rule, all these symptoms do not require additional therapeutic measures: they disappear within 24 hours. In rare cases, the following may be prescribed: Diazepam or Nitrazepam - for sleep disturbances, drugs with antihypertensive effects - for high blood pressure.
Evaluation of the effectiveness of treatment with Neurox and Mexidol
